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EPIC: Inferring relevant cell types for complex traits by integrating genome-wide association studies and single-cell RNA sequencing

More than a decade of genome-wide association studies (GWASs) have identified genetic risk variants that are significantly associated with complex traits. Emerging evidence suggests that the function of trait-associated variants likely acts in a tissue- or cell-type-specific fashion. Yet, it remains...

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Detalles Bibliográficos
Autores principales:	Wang, Rujin, Lin, Dan-Yu, Jiang, Yuchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242467/ https://www.ncbi.nlm.nih.gov/pubmed/35709291 http://dx.doi.org/10.1371/journal.pgen.1010251

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