Complex Inheritance of Rare Missense Variants in PAK2, TAP2, and PLCL1 Genes in a Consanguineous Arab Family With Multiple Autoimmune Diseases Including Celiac Disease

BACKGROUND: Autoimmune diseases (AIDs) share a common molecular etiology and often present overlapping clinical presentations. Thus, this study aims to explore the complex molecular basis of AID by whole exome sequencing and computational biology analysis. METHODS: Molecular screening of the consang...

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Detalles Bibliográficos
Autores principales: Alharthi, Arwa Mastoor, Banaganapalli, Babajan, Hassan, Sabah M., Rashidi, Omran, Al-Shehri, Bandar Ali, Alaifan, Meshari A., Alhussaini, Bakr H., Alsufyani, Hadeel A., Alghamdi, Kawthar Saad, Nasser, Khalda Khalid, Bin-Taleb, Yagoub, Elango, Ramu, Shaik, Noor Ahmad, Saadah, Omar I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242504/
https://www.ncbi.nlm.nih.gov/pubmed/35783297
http://dx.doi.org/10.3389/fped.2022.895298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242504/
https://www.ncbi.nlm.nih.gov/pubmed/35783297
http://dx.doi.org/10.3389/fped.2022.895298

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