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Biological chemotaxis-guided self-thermophoretic nanoplatform augments colorectal cancer therapy through autonomous mucus penetration

Oral drug delivery systems have great potential to treat colorectal cancer (CRC). However, the drug delivery efficiency is restricted by limited CRC-related intestine positioning and dense mucus barrier. Here, we present a biological chemotaxis-guided self-thermophoretic nanoplatform that facilitate...

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Detalles Bibliográficos
Autores principales: Wang, Zhi-Hao, Chu, Mengyu, Yin, Na, Huang, Wanting, Liu, Wei, Zhang, Zhenzhong, Liu, Junjie, Shi, Jinjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242589/
https://www.ncbi.nlm.nih.gov/pubmed/35767627
http://dx.doi.org/10.1126/sciadv.abn3917