The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor

Dynein harnesses ATP hydrolysis to move cargo on microtubules in multiple biological contexts. Dynein meets a unique challenge in meiosis by moving chromosomes tethered to the nuclear envelope to facilitate homolog pairing essential for gametogenesis. Though processive dynein motility requires bindi...

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Detalles Bibliográficos
Autores principales: Agrawal, Ritvija, Gillies, John P, Zang, Juliana L, Zhang, Jingjing, Garrott, Sharon R, Shibuya, Hiroki, Nandakumar, Jayakrishnan, DeSantis, Morgan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242646/
https://www.ncbi.nlm.nih.gov/pubmed/35703493
http://dx.doi.org/10.7554/eLife.78201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242646/
https://www.ncbi.nlm.nih.gov/pubmed/35703493
http://dx.doi.org/10.7554/eLife.78201

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