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The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor
Dynein harnesses ATP hydrolysis to move cargo on microtubules in multiple biological contexts. Dynein meets a unique challenge in meiosis by moving chromosomes tethered to the nuclear envelope to facilitate homolog pairing essential for gametogenesis. Though processive dynein motility requires bindi...
Autores principales: | Agrawal, Ritvija, Gillies, John P, Zang, Juliana L, Zhang, Jingjing, Garrott, Sharon R, Shibuya, Hiroki, Nandakumar, Jayakrishnan, DeSantis, Morgan E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242646/ https://www.ncbi.nlm.nih.gov/pubmed/35703493 http://dx.doi.org/10.7554/eLife.78201 |
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