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ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids

Branched fatty acid (FA) esters of hydroxy FAs (HFAs; FAHFAs) are recently discovered lipids that are conserved from yeast to mammals(1,2). A subfamily, palmitic acid esters of hydroxy stearic acids (PAHSAs), are anti-inflammatory and anti-diabetic(1,3). Humans and mice with insulin resistance have...

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Detalles Bibliográficos
Autores principales: Patel, Rucha, Santoro, Anna, Hofer, Peter, Tan, Dan, Oberer, Monika, Nelson, Andrew T., Konduri, Srihari, Siegel, Dionicio, Zechner, Rudolf, Saghatelian, Alan, Kahn, Barbara B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242854/
https://www.ncbi.nlm.nih.gov/pubmed/35676490
http://dx.doi.org/10.1038/s41586-022-04787-x