Structural basis of sodium-dependent bile salt uptake into the liver

The liver takes up bile salts from blood to generate bile, enabling absorption of lipophilic nutrients and excretion of metabolites and drugs(1). Human Na(+)–taurocholate co-transporting polypeptide (NTCP) is the main bile salt uptake system in liver. NTCP is also the cellular entry receptor of huma...

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Detalles Bibliográficos
Autores principales: Goutam, Kapil, Ielasi, Francesco S., Pardon, Els, Steyaert, Jan, Reyes, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242856/
https://www.ncbi.nlm.nih.gov/pubmed/35545671
http://dx.doi.org/10.1038/s41586-022-04723-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242856/
https://www.ncbi.nlm.nih.gov/pubmed/35545671
http://dx.doi.org/10.1038/s41586-022-04723-z

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