D609 inhibition of phosphatidylcholine-specific phospholipase C attenuates prolonged insulin stimulation-mediated GLUT4 downregulation in 3T3-L1 adipocytes

Glucose uptake is stimulated by insulin via stimulation of glucose transporter 4 (GLUT4) translocation to the plasma membrane from intracellular compartments in adipose tissue and muscles. Insulin stimulation for prolonged periods depletes GLUT4 protein, particularly in highly insulin-responsive GLU...

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Detalles Bibliográficos
Autores principales: Ma, Jinhui, Zhang, Xu, Song, Yankun, Qin, Yan, Tan, Yinghui, Zheng, Lishuang, Cheng, Baoqian, Xi, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242966/
https://www.ncbi.nlm.nih.gov/pubmed/35048323
http://dx.doi.org/10.1007/s13105-022-00872-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242966/
https://www.ncbi.nlm.nih.gov/pubmed/35048323
http://dx.doi.org/10.1007/s13105-022-00872-x

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