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Pervasive translation of circular RNAs driven by short IRES-like elements

Some circular RNAs (circRNAs) were found to be translated through IRES-driven mechanism, however the scope and functions of circRNA translation are unclear because endogenous IRESs are rare. To determine the prevalence and mechanism of circRNA translation, we develop a cell-based system to screen ra...

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Detalles Bibliográficos
Autores principales: Fan, Xiaojuan, Yang, Yun, Chen, Chuyun, Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242994/
https://www.ncbi.nlm.nih.gov/pubmed/35768398
http://dx.doi.org/10.1038/s41467-022-31327-y