Quantum-dot-labeled synuclein seed assay identifies drugs modulating the experimental prion-like transmission

Synucleinopathies are neurodegenerative disorders including Parkinson disease (PD), dementia with Lewy body (DLB), and multiple system atrophy (MSA) that involve deposits of the protein alpha-synuclein (α-syn) in the brain. The inoculation of α-syn aggregates derived from synucleinopathy or preforme...

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Detalles Bibliográficos
Autores principales: Imamura, Yukio, Okuzumi, Ayami, Yoshinaga, Saki, Hiyama, Akiko, Furukawa, Yoshiaki, Miyasaka, Tomohiro, Hattori, Nobutaka, Nukina, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243017/
https://www.ncbi.nlm.nih.gov/pubmed/35768587
http://dx.doi.org/10.1038/s42003-022-03590-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243017/
https://www.ncbi.nlm.nih.gov/pubmed/35768587
http://dx.doi.org/10.1038/s42003-022-03590-8

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