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Quantum-dot-labeled synuclein seed assay identifies drugs modulating the experimental prion-like transmission

Synucleinopathies are neurodegenerative disorders including Parkinson disease (PD), dementia with Lewy body (DLB), and multiple system atrophy (MSA) that involve deposits of the protein alpha-synuclein (α-syn) in the brain. The inoculation of α-syn aggregates derived from synucleinopathy or preforme...

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Detalles Bibliográficos
Autores principales:	Imamura, Yukio, Okuzumi, Ayami, Yoshinaga, Saki, Hiyama, Akiko, Furukawa, Yoshiaki, Miyasaka, Tomohiro, Hattori, Nobutaka, Nukina, Nobuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243017/ https://www.ncbi.nlm.nih.gov/pubmed/35768587 http://dx.doi.org/10.1038/s42003-022-03590-8

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