LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response

The hypoxic ventilatory response (HVR) is critical to breathing and thus oxygen supply to the body and is primarily mediated by the carotid bodies. Here we reveal that carotid body afferent discharge during hypoxia and hypercapnia is determined by the expression of Liver Kinase B1 (LKB1), the princi...

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Detalles Bibliográficos
Autores principales: MacMillan, Sandy, Holmes, Andrew P., Dallas, Mark L., Mahmoud, Amira D., Shipston, Michael J., Peers, Chris, Hardie, D. Grahame, Kumar, Prem, Evans, A. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243028/
https://www.ncbi.nlm.nih.gov/pubmed/35768580
http://dx.doi.org/10.1038/s42003-022-03583-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243028/
https://www.ncbi.nlm.nih.gov/pubmed/35768580
http://dx.doi.org/10.1038/s42003-022-03583-7

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