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On the prebiotic selection of nucleotide anomers: A computational study

Present-day known predominance of the β- over the α-anomers in nucleosides and nucleotides emerges from a thermodynamic analysis of their assembly from their components, i.e. bases, sugars, and a phosphate group. Furthermore, the incorporation of uracil into RNA and thymine into DNA rather than the...

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Detalles Bibliográficos
Autores principales: Castanedo, Lázaro A.M., Matta, Chérif F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243047/
https://www.ncbi.nlm.nih.gov/pubmed/35785221
http://dx.doi.org/10.1016/j.heliyon.2022.e09657