Cargando…

A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine

We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain conjugated with conserved M2e epitopes to overcome the drawbacks of low efficacy by monomeric domain-based universal vaccines. M2e-H3 stalk protein expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Subbiah, Jeeva, Oh, Judy, Kim, Ki-Hye, Shin, Chong-Hyun, Park, Bo Ryoung, Bhatnagar, Noopur, Seong, Baik-Lin, Wang, Bao-Zhong, Kang, Sang-Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243060/
https://www.ncbi.nlm.nih.gov/pubmed/35768475
http://dx.doi.org/10.1038/s41541-022-00498-6