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A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine

We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain conjugated with conserved M2e epitopes to overcome the drawbacks of low efficacy by monomeric domain-based universal vaccines. M2e-H3 stalk protein expres...

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Detalles Bibliográficos
Autores principales:	Subbiah, Jeeva, Oh, Judy, Kim, Ki-Hye, Shin, Chong-Hyun, Park, Bo Ryoung, Bhatnagar, Noopur, Seong, Baik-Lin, Wang, Bao-Zhong, Kang, Sang-Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243060/ https://www.ncbi.nlm.nih.gov/pubmed/35768475 http://dx.doi.org/10.1038/s41541-022-00498-6

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