WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage

Perturbation in the replication-stress response (RSR) and DNA-damage response (DDR) causes genomic instability. Genomic instability occurs in Wiskott-Aldrich syndrome (WAS), a primary immunodeficiency disorder, yet the mechanism remains largely uncharacterized. Replication protein A (RPA), a single-...

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Detalles Bibliográficos
Autores principales: Han, Seong-Su, Wen, Kuo-Kuang, García-Rubio, María L., Wold, Marc S., Aguilera, Andrés, Niedzwiedz, Wojciech, Vyas, Yatin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243104/
https://www.ncbi.nlm.nih.gov/pubmed/35768435
http://dx.doi.org/10.1038/s41467-022-31415-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243104/
https://www.ncbi.nlm.nih.gov/pubmed/35768435
http://dx.doi.org/10.1038/s41467-022-31415-z

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