Inactivation of the Hippo tumor suppressor pathway promotes melanoma

Melanoma is commonly driven by activating mutations in the MAP kinase BRAF; however, oncogenic BRAF alone is insufficient to promote melanomagenesis. Instead, its expression induces a transient proliferative burst that ultimately ceases with the development of benign nevi comprised of growth-arreste...

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Detalles Bibliográficos
Autores principales: Vittoria, Marc A., Kingston, Nathan, Kotynkova, Kristyna, Xia, Eric, Hong, Rui, Huang, Lee, McDonald, Shayna, Tilston-Lunel, Andrew, Darp, Revati, Campbell, Joshua D., Lang, Deborah, Xu, Xiaowei, Ceol, Craig J., Varelas, Xaralabos, Ganem, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243107/
https://www.ncbi.nlm.nih.gov/pubmed/35768444
http://dx.doi.org/10.1038/s41467-022-31399-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243107/
https://www.ncbi.nlm.nih.gov/pubmed/35768444
http://dx.doi.org/10.1038/s41467-022-31399-w

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