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Inactivation of the Hippo tumor suppressor pathway promotes melanoma

Melanoma is commonly driven by activating mutations in the MAP kinase BRAF; however, oncogenic BRAF alone is insufficient to promote melanomagenesis. Instead, its expression induces a transient proliferative burst that ultimately ceases with the development of benign nevi comprised of growth-arreste...

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Detalles Bibliográficos
Autores principales:	Vittoria, Marc A., Kingston, Nathan, Kotynkova, Kristyna, Xia, Eric, Hong, Rui, Huang, Lee, McDonald, Shayna, Tilston-Lunel, Andrew, Darp, Revati, Campbell, Joshua D., Lang, Deborah, Xu, Xiaowei, Ceol, Craig J., Varelas, Xaralabos, Ganem, Neil J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243107/ https://www.ncbi.nlm.nih.gov/pubmed/35768444 http://dx.doi.org/10.1038/s41467-022-31399-w

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