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Limited effects of m(6)A modification on mRNA partitioning into stress granules

The presence of the m(6)A modification in mammalian mRNAs is proposed to promote mRNA recruitment to stress granules through the interaction with YTHDF proteins. We test this possibility by examining the accumulation of mRNAs in stress granules in both WT and ∆METTL3 mES cells, which are deficient i...

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Detalles Bibliográficos
Autores principales: Khong, Anthony, Matheny, Tyler, Huynh, Thao Ngoc, Babl, Vincent, Parker, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243116/
https://www.ncbi.nlm.nih.gov/pubmed/35768440
http://dx.doi.org/10.1038/s41467-022-31358-5