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Increased acid sphingomyelinase levels in pediatric patients with obesity

The level of secretory acid sphingomyelinase (S-ASM), a key enzyme in the sphingolipid metabolism, is elevated in a variety of human diseases, including in the serum of obese adults. Alterations in S-ASM were also found to induce morphological changes in erythrocytes. Consequently, the inhibition of...

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Detalles Bibliográficos
Autores principales: Mameli, Chiara, Carnovale, Carla, Ambrogi, Federico, Infante, Gabriele, Biejat, Paulina Roux, Napoli, Alessandra, Coazzoli, Marco, Calcaterra, Valeria, Schneider, Laura, Perazzi, Chiara, Zuccotti, Gianvincenzo, Clementi, Emilio, Moscheni, Claudia, Perrotta, Cristiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243121/
https://www.ncbi.nlm.nih.gov/pubmed/35768443
http://dx.doi.org/10.1038/s41598-022-14687-9