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Increased acid sphingomyelinase levels in pediatric patients with obesity
The level of secretory acid sphingomyelinase (S-ASM), a key enzyme in the sphingolipid metabolism, is elevated in a variety of human diseases, including in the serum of obese adults. Alterations in S-ASM were also found to induce morphological changes in erythrocytes. Consequently, the inhibition of...
Autores principales: | Mameli, Chiara, Carnovale, Carla, Ambrogi, Federico, Infante, Gabriele, Biejat, Paulina Roux, Napoli, Alessandra, Coazzoli, Marco, Calcaterra, Valeria, Schneider, Laura, Perazzi, Chiara, Zuccotti, Gianvincenzo, Clementi, Emilio, Moscheni, Claudia, Perrotta, Cristiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243121/ https://www.ncbi.nlm.nih.gov/pubmed/35768443 http://dx.doi.org/10.1038/s41598-022-14687-9 |
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