Inhibitory effects of Triphala on CYP isoforms in vitro and its pharmacokinetic interactions with phenacetin and midazolam in rats

CONTEXT: Direct evidence of Triphala-drug interactions has not been provided to date. OBJECTIVE: This study was aimed to determine the effects of Triphala on cytochrome P450 (CYP) isoforms and P-glycoprotein (P-gp) in vitro, and to investigate pharmacokinetic interactions of Triphala with CYP-probes...

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Detalles Bibliográficos
Autores principales: Nontakham, Jannarin, Siripong, Pongpun, Sato, Hitoshi, Chewchinda, Savita, Arunrungvichian, Kuntarat, Yahuafai, Jantana, Goli, Arman Syah, Sato, Vilasinee Hirunpanich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243172/
https://www.ncbi.nlm.nih.gov/pubmed/35785236
http://dx.doi.org/10.1016/j.heliyon.2022.e09764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243172/
https://www.ncbi.nlm.nih.gov/pubmed/35785236
http://dx.doi.org/10.1016/j.heliyon.2022.e09764

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