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Inhibitory effects of Triphala on CYP isoforms in vitro and its pharmacokinetic interactions with phenacetin and midazolam in rats
CONTEXT: Direct evidence of Triphala-drug interactions has not been provided to date. OBJECTIVE: This study was aimed to determine the effects of Triphala on cytochrome P450 (CYP) isoforms and P-glycoprotein (P-gp) in vitro, and to investigate pharmacokinetic interactions of Triphala with CYP-probes...
Autores principales: | Nontakham, Jannarin, Siripong, Pongpun, Sato, Hitoshi, Chewchinda, Savita, Arunrungvichian, Kuntarat, Yahuafai, Jantana, Goli, Arman Syah, Sato, Vilasinee Hirunpanich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243172/ https://www.ncbi.nlm.nih.gov/pubmed/35785236 http://dx.doi.org/10.1016/j.heliyon.2022.e09764 |
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