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Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemomechanical properties despite bearing the same myosin heavy chain isoform

The myosin II motors are ATP-powered force-generating machines driving cardiac and muscle contraction. Myosin II heavy chain isoform-beta (β-MyHC) is primarily expressed in the ventricular myocardium and in slow-twitch muscle fibers, such as M. soleus. M. soleus–derived myosin II (SolM-II) is often...

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Detalles Bibliográficos
Autores principales: Wang, Tianbang, Spahiu, Emrulla, Osten, Jennifer, Behrens, Florentine, Grünhagen, Fabius, Scholz, Tim, Kraft, Theresia, Nayak, Arnab, Amrute-Nayak, Mamta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243179/
https://www.ncbi.nlm.nih.gov/pubmed/35623390
http://dx.doi.org/10.1016/j.jbc.2022.102070