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Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I

The ubiquinone (UQ) reduction step catalyzed by NADH-UQ oxidoreductase (mitochondrial respiratory complex I) is key to triggering proton translocation across the inner mitochondrial membrane. Structural studies have identified a long, narrow, UQ-accessing tunnel within the enzyme. We previously demo...

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Detalles Bibliográficos
Autores principales: Uno, Shinpei, Masuya, Takahiro, Zdorevskyi, Oleksii, Ikunishi, Ryo, Shinzawa-Itoh, Kyoko, Lasham, Jonathan, Sharma, Vivek, Murai, Masatoshi, Miyoshi, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243180/
https://www.ncbi.nlm.nih.gov/pubmed/35643318
http://dx.doi.org/10.1016/j.jbc.2022.102075