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Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I
The ubiquinone (UQ) reduction step catalyzed by NADH-UQ oxidoreductase (mitochondrial respiratory complex I) is key to triggering proton translocation across the inner mitochondrial membrane. Structural studies have identified a long, narrow, UQ-accessing tunnel within the enzyme. We previously demo...
Autores principales: | Uno, Shinpei, Masuya, Takahiro, Zdorevskyi, Oleksii, Ikunishi, Ryo, Shinzawa-Itoh, Kyoko, Lasham, Jonathan, Sharma, Vivek, Murai, Masatoshi, Miyoshi, Hideto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243180/ https://www.ncbi.nlm.nih.gov/pubmed/35643318 http://dx.doi.org/10.1016/j.jbc.2022.102075 |
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