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R-loop Mediated DNA Damage and Impaired DNA Repair in Spinal Muscular Atrophy
Defects in DNA repair pathways are a major cause of DNA damage accumulation leading to genomic instability and neurodegeneration. Efficient DNA damage repair is critical to maintain genomicstability and support cell function and viability. DNA damage results in the activation of cell death pathways,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243258/ https://www.ncbi.nlm.nih.gov/pubmed/35783101 http://dx.doi.org/10.3389/fncel.2022.826608 |