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An Efficient UPLC-MS/MS Method Established to Detect Relugolix Concentration in Rat Plasma

Relugolix, a gonadotropin-releasing hormone (GnRH) receptor antagonist, has been well studied in the treatment of endometriosis symptomatic. It is mainly metabolized by the CYP3A subfamily of P450 enzymes, while minorly metabolized by CYP2C8. Daidzein in different dose groups exhibited a certain ind...

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Detalles Bibliográficos
Autores principales: Xing, Liying, Liu, Ya-nan, Yao, Hongye, Wang, Tingting, Xie, Fuchen, Luo, Shunbin, Luo, Pingping, Tang, Shengling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243301/
https://www.ncbi.nlm.nih.gov/pubmed/35784757
http://dx.doi.org/10.3389/fphar.2022.874973