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Tumor-Specific CD4(+) T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4(–) T Cells

Cytotoxic CD8(+) T cells are the main focus of efforts to understand anti-tumor immunity and immunotherapy. The adoptive transfer of tumor-reactive cytotoxic CD8(+) T lymphocytes expanded and differentiated in vitro has long been considered the primary strategy in adaptive anti-tumor immunity, howev...

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Detalles Bibliográficos
Autores principales: Liu, Qiao, Wang, Lisha, Lin, Huayu, Wang, Zhiming, Wu, Jialin, Guo, Junyi, Wen, Shuqiong, Ran, Ling, Yue, Zhengliang, Su, Xingxing, Wu, Qing, Tang, Jianfang, Li, Zhirong, Hu, Li, Xu, Lifan, Ye, Lilin, Huang, Qizhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243303/
https://www.ncbi.nlm.nih.gov/pubmed/35784297
http://dx.doi.org/10.3389/fimmu.2022.875718