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Tumor-Specific CD4(+) T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4(–) T Cells
Cytotoxic CD8(+) T cells are the main focus of efforts to understand anti-tumor immunity and immunotherapy. The adoptive transfer of tumor-reactive cytotoxic CD8(+) T lymphocytes expanded and differentiated in vitro has long been considered the primary strategy in adaptive anti-tumor immunity, howev...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243303/ https://www.ncbi.nlm.nih.gov/pubmed/35784297 http://dx.doi.org/10.3389/fimmu.2022.875718 |