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The Correlation Between Busulfan Exposure and Clinical Outcomes in Chinese Pediatric Patients: A Population Pharmacokinetic Study

Aims: The aims of the study were to 1) establish a population pharmacokinetic (Pop-PK) model for busulfan in Chinese pediatric patients undergoing hematopoietic stem cell transplantation (HSCT) and then estimate busulfan exposure and 2) explore the association between busulfan exposure and clinical...

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Detalles Bibliográficos
Autores principales: Du, Xiaohuan, Huang, Chenrong, Xue, Ling, Jiao, Zheng, Zhu, Min, Li, Jie, Lu, Jun, Xiao, Peifang, Zhou, Xuemei, Mao, Chenmei, Zhu, Zengyan, Dong, Ji, Liu, Xiaoxue, Chen, Zhiyao, Zhang, Shichao, Ding, Yiduo, Hu, Shaoyan, Miao, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243314/
https://www.ncbi.nlm.nih.gov/pubmed/35784763
http://dx.doi.org/10.3389/fphar.2022.905879