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Vitamin D receptor (VDR) contributes to the development of hypercalciuria by sensitizing VDR target genes to vitamin D in a genetic hypercalciuric stone-forming (GHS) rat model

Human idiopathic hypercalciuria (IH) is the most common cause of calcium oxalate nephrolithiasis with perturbed calcium metabolism with increased bone resorption and decreased renal calcium reabsorption, which can be phenotype-copied in the genetic hypercalciuric stone-forming (GHS) rat model. We pr...

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Detalles Bibliográficos
Autores principales: Guo, Shang, Chia, Weekai, Wang, Hongwei, Bushinsky, David A., Zhong, Biao, Favus, Murray J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243318/
https://www.ncbi.nlm.nih.gov/pubmed/35782986
http://dx.doi.org/10.1016/j.gendis.2020.09.001