Hepatic SIRT6 deficit promotes liver tumorigenesis in the mice models

SIRT6 belongs to class III sirtuin family with NAD+-dependent histone deacetylase activities and controls multiple processes including aging, metabolism and inflammation. In recent years, increasing studies showed tumor suppressor role of SIRT6 in HCC development. We established a two-stage DEN foll...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Lan, Linhua, Yang, Fan, Jiang, Shan, Xu, Haojun, Zhang, Chengfei, Zhou, Guoren, Xia, Hongping, Xia, Jinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243323/
https://www.ncbi.nlm.nih.gov/pubmed/35782983
http://dx.doi.org/10.1016/j.gendis.2020.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243323/
https://www.ncbi.nlm.nih.gov/pubmed/35782983
http://dx.doi.org/10.1016/j.gendis.2020.08.007

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