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Liver-specific Mettl3 ablation delays liver regeneration in mice

This study investigated the role of N6-methyladenosine RNA methylation in liver regeneration following partial hepatectomy in mice. We created a liver-specific knockout mouse model by the deletion of Mettl3, a key component of the N6-methyladenosine methyltransferase complex, using the albumin-Cre s...

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Detalles Bibliográficos
Autores principales: Meng, Jiaxiang, Zhao, Zhicong, Xi, Zhifeng, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243324/
https://www.ncbi.nlm.nih.gov/pubmed/35782970
http://dx.doi.org/10.1016/j.gendis.2020.11.002