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Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms

Neurodegenerative diseases (NDs) involve complex cellular mechanisms that are incompletely understood. Emerging findings have revealed that disruption of nuclear processes play key roles in ND pathogenesis. The nucleus is a nexus for gene regulation and cellular processes that together, may underlie...

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Detalles Bibliográficos
Autores principales: Nelson, Ruth S., Dammer, Eric B., Santiago, Juliet V., Seyfried, Nicholas T., Rangaraju, Srikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243337/
https://www.ncbi.nlm.nih.gov/pubmed/35784845
http://dx.doi.org/10.3389/fnins.2022.902146