Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development

The deltex family protein DTX3 is believed to possess E3 ubiquitin ligase activity, as it contains a classic RING finger domain. However, its biological role and the underlying mechanism in cancer remain largely elusive. Here, we identified DTX3 as a novel mutant p53-interacting protein in ovarian c...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Hao, Qian, Li, Jiajia, Chen, Yajie, Lu, Hua, Wu, Xiaohua, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243342/
https://www.ncbi.nlm.nih.gov/pubmed/35782979
http://dx.doi.org/10.1016/j.gendis.2020.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243342/
https://www.ncbi.nlm.nih.gov/pubmed/35782979
http://dx.doi.org/10.1016/j.gendis.2020.11.007

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