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The mevalonate pathway promotes the metastasis of osteosarcoma by regulating YAP1 activity via RhoA

Osteosarcoma is the most common malignant bone tumour, and the metastasis of osteosarcoma is an important cause of death. Evidence has shown that the mevalonate pathway is highly activated and is expected to be a new target for tumour therapy. In this study, we investigated the effect of mevalonate...

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Detalles Bibliográficos
Autores principales: Du, Xing, Ou, Yunsheng, Zhang, Muzi, Li, Kai, Huang, Wei, Jiang, Dianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243346/
https://www.ncbi.nlm.nih.gov/pubmed/35782968
http://dx.doi.org/10.1016/j.gendis.2020.11.009