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Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair

DNA mismatch repair (MMR) repairs replication errors, and MMR defects play a role in both inherited cancer predisposition syndromes and in sporadic cancers. MMR also recognizes mispairs caused by environmental and chemotherapeutic agents; however, in these cases mispair recognition leads to apoptosi...

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Detalles Bibliográficos
Autores principales: Miller, Anna K., Mao, Guogen, Knicely, Breanna G., Daniels, Hannah G., Rahal, Christine, Putnam, Christopher D., Kolodner, Richard D., Goellner, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243396/
https://www.ncbi.nlm.nih.gov/pubmed/35784486
http://dx.doi.org/10.3389/fcell.2022.843121