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Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair
DNA mismatch repair (MMR) repairs replication errors, and MMR defects play a role in both inherited cancer predisposition syndromes and in sporadic cancers. MMR also recognizes mispairs caused by environmental and chemotherapeutic agents; however, in these cases mispair recognition leads to apoptosi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243396/ https://www.ncbi.nlm.nih.gov/pubmed/35784486 http://dx.doi.org/10.3389/fcell.2022.843121 |