Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts

Alzheimer’s disease (AD) is a genetic and sporadic neurodegenerative disease characterized by extracellular amyloid-β-protein (Aβ) aggregates as amyloid plaques and neuronal loss in the brain parenchyma of patients. Familial AD (FAD) is found to be genetically linked to missense mutations either in...

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Detalles Bibliográficos
Autores principales: Zou, Kun, Islam, Sadequl, Sun, Yang, Gao, Yuan, Nakamura, Tomohisa, Komano, Hiroto, Tomita, Taisuke, Michikawa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243443/
https://www.ncbi.nlm.nih.gov/pubmed/35783133
http://dx.doi.org/10.3389/fnagi.2022.902525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243443/
https://www.ncbi.nlm.nih.gov/pubmed/35783133
http://dx.doi.org/10.3389/fnagi.2022.902525

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