Ketone Bodies Improve Human CD8(+) Cytotoxic T-Cell Immune Response During COVID-19 Infection

Severe COVID-19 is characterized by profound CD8(+) T-cell dysfunction, which cannot be specifically treated to date. We here investigate whether metabolic CD8(+) T-cell reprogramming by ketone bodies could be a promising strategy to overcome the immunoparalysis in COVID-19 patients. This approach w...

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Detalles Bibliográficos
Autores principales: Hirschberger, Simon, Gellert, Luca, Effinger, David, Muenchhoff, Maximilian, Herrmann, Markus, Briegel, Josef-Maria, Zwißler, Bernhard, Kreth, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243504/
https://www.ncbi.nlm.nih.gov/pubmed/35783654
http://dx.doi.org/10.3389/fmed.2022.923502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243504/
https://www.ncbi.nlm.nih.gov/pubmed/35783654
http://dx.doi.org/10.3389/fmed.2022.923502

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