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Conserved Amino Acids Residing Outside the Voltage Field Can Shift the Voltage Sensitivity and Increase the Signal Speed and Size of Ciona Based GEVIs

To identify potential regions of the voltage-sensing domain that could shift the voltage sensitivity of Ciona intestinalis based Genetically Encoded Voltage Indicators (GEVIs), we aligned the amino acid sequences of voltage-gated sodium channels from different organisms. Conserved polar residues wer...

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Detalles Bibliográficos
Autores principales: Sepehri Rad, Masoud, Cohen, Lawrence B., Baker, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243531/
https://www.ncbi.nlm.nih.gov/pubmed/35784472
http://dx.doi.org/10.3389/fcell.2022.868143