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Effects of Sarcolemmal Background Ca(2+) Entry and Sarcoplasmic Ca(2+) Leak Currents on Electrophysiology and Ca(2+) Transients in Human Ventricular Cardiomyocytes: A Computational Comparison
The intricate regulation of the compartmental Ca(2+) concentrations in cardiomyocytes is critical for electrophysiology, excitation-contraction coupling, and other signaling pathways. Research into the complex signaling pathways is motivated by cardiac pathologies including arrhythmia and maladaptiv...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243544/ https://www.ncbi.nlm.nih.gov/pubmed/35784869 http://dx.doi.org/10.3389/fphys.2022.916278 |