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Development of an HIV reporter virus that identifies latently infected CD4(+) T cells

There is no cure for HIV infection, as the virus establishes a latent reservoir, which escapes highly active antiretroviral treatments. One major obstacle is the difficulty identifying cells that harbor latent proviruses. We devised a single-round viral vector that carries a series of versatile repo...

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Detalles Bibliográficos
Autores principales: Kim, Eun Hye, Manganaro, Lara, Schotsaert, Michael, Brown, Brian D., Mulder, Lubbertus C.F., Simon, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243624/
https://www.ncbi.nlm.nih.gov/pubmed/35784650
http://dx.doi.org/10.1016/j.crmeth.2022.100238