Cargando…
Development of an HIV reporter virus that identifies latently infected CD4(+) T cells
There is no cure for HIV infection, as the virus establishes a latent reservoir, which escapes highly active antiretroviral treatments. One major obstacle is the difficulty identifying cells that harbor latent proviruses. We devised a single-round viral vector that carries a series of versatile repo...
Autores principales: | Kim, Eun Hye, Manganaro, Lara, Schotsaert, Michael, Brown, Brian D., Mulder, Lubbertus C.F., Simon, Viviana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243624/ https://www.ncbi.nlm.nih.gov/pubmed/35784650 http://dx.doi.org/10.1016/j.crmeth.2022.100238 |
Ejemplares similares
-
ISG15 deficiency restricts HIV-1 infection
por: Jurczyszak, Denise, et al.
Publicado: (2022) -
Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling
por: Morrison, Juliet, et al.
Publicado: (2013) -
Transcriptional Regulation of Latent Feline Immunodeficiency Virus in Peripheral CD4+ T-lymphocytes
por: McDonnel, Samantha J., et al.
Publicado: (2012) -
SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection
por: Berger, André, et al.
Publicado: (2011) -
Activation and lysis of human CD4 cells latently infected with HIV-1
por: Pegu, Amarendra, et al.
Publicado: (2015)