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EV71 3C protease cleaves host anti-viral factor OAS3 and enhances virus replication

The global spread of enteroviruses (EVs) has become more frequent, severe and life-threatening. Intereron (IFN) I has been proved to control EVs by regulating IFN-stimulated genes (ISG) expression. 2′-5′-oligoadenylate synthetases 3 (OAS3) is an important ISG in the OAS/RNase L antiviral system. The...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaolei, Tian, Li, Wang, Jian, Zheng, Baisong, Zhang, Wenyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243667/
https://www.ncbi.nlm.nih.gov/pubmed/35504537
http://dx.doi.org/10.1016/j.virs.2022.04.013