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Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens

Generalized modules for membrane antigens (GMMA) are exosomes released from engineered Gram-negative bacteria and represent an attractive vaccine platform for the delivery of the O-Antigen (OAg), recognized as the key target for protective immunity against several pathogens such as Shigella. Shigell...

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Detalles Bibliográficos
Autores principales: Gasperini, Gianmarco, Raso, Maria Michelina, Schiavo, Fabiola, Aruta, Maria Grazia, Ravenscroft, Neil, Bellich, Barbara, Cescutti, Paola, Necchi, Francesca, Rappuoli, Rino, Micoli, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243986/
https://www.ncbi.nlm.nih.gov/pubmed/35773292
http://dx.doi.org/10.1038/s41541-022-00497-7