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Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens
Generalized modules for membrane antigens (GMMA) are exosomes released from engineered Gram-negative bacteria and represent an attractive vaccine platform for the delivery of the O-Antigen (OAg), recognized as the key target for protective immunity against several pathogens such as Shigella. Shigell...
Autores principales: | Gasperini, Gianmarco, Raso, Maria Michelina, Schiavo, Fabiola, Aruta, Maria Grazia, Ravenscroft, Neil, Bellich, Barbara, Cescutti, Paola, Necchi, Francesca, Rappuoli, Rino, Micoli, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243986/ https://www.ncbi.nlm.nih.gov/pubmed/35773292 http://dx.doi.org/10.1038/s41541-022-00497-7 |
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