The Activation of Protamine 1 Using Epigenome Editing Decreases the Proliferation of Tumorigenic Cells

DNA methyltransferases (DNMT) and histone deacetylases (HDAC) inhibitors are used as cancer epigenome drugs. However, these epigenetic drugs lack targeting specificity and could risk inducing genome instability and the expression of oncogenes. Therefore, there is a need to develop new therapeutic st...

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Detalles Bibliográficos
Autores principales: Namous, Hadjer, Braz, Camila Urbano, Wang, Yiding, Khatib, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244402/
https://www.ncbi.nlm.nih.gov/pubmed/35783678
http://dx.doi.org/10.3389/fgeed.2022.844904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244402/
https://www.ncbi.nlm.nih.gov/pubmed/35783678
http://dx.doi.org/10.3389/fgeed.2022.844904

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