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Minocycline Reduces Hypothalamic Microglia Activation and Improves Metabolic Dysfunction in High Fat Diet-Induced Obese Mice

Obesity is associated with insulin resistance, glucose intolerance, inflammation, and altered neuronal activity in brain regions controlling metabolic functions including food intake, energy expenditure, and glucose homeostasis, such as the hypothalamus. In this study, we tested the hypothesis that...

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Detalles Bibliográficos
Autores principales: Coker, Caitlin R., White, Melissa, Singal, Aneesh, Bingaman, Sarah S., Paul, Anirban, Arnold, Amy C., Silberman, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244633/
https://www.ncbi.nlm.nih.gov/pubmed/35784876
http://dx.doi.org/10.3389/fphys.2022.933706