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Helios Expression Is Downregulated on CD8(+) Treg in Two Mouse Models of Lupus During Disease Progression
T-cell–mediated autoimmunity reflects an imbalance in this compartment that is not restored by tolerogenic immune cells, e.g., regulatory T cells or tolerogenic dendritic cells (tolDCs). Although studies into T-cell equilibrium have mainly focused on regulatory CD4(+)FoxP3(+) T cells (CD4(+) Tregs),...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244697/ https://www.ncbi.nlm.nih.gov/pubmed/35784310 http://dx.doi.org/10.3389/fimmu.2022.922958 |